NFL: Los Angeles Chargers vs Indianapolis Colts 19/10/2025
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Los Angeles Chargers

Indianapolis Colts
SoFi Stadium (Inglewood, CA), 18:00 @ 19.10.2025
Betting on Point margin
Last week the Colts ruined my teaser. Before the game even started, they lost two players to injury — one during warm-up — and their depleted defense made Arizona Cardinals’ backup quarterback Jacoby Brissett look like Tom Brady.
In the latest Colts injury report, I see the same defensive absences, and now they’ll face the excellent Justin Herbert, who can easily throw for 400 yards and 3–4 touchdowns. Not that the Chargers’ defense is any healthier — they’ll also have to deal with the unstoppable Colts offense.
I believe this is a game that can easily reach the 50s and maybe even touch the 60s.
I took Over 48.5 and hope for a shootout.
Los Angeles Chargers vs Indianapolis Colts | Over 48.5
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